| 标题： | 中国人群食管癌风险管理公众指南 |
| title： | Chinese Public Guideline for the Management of Esophageal Cancer |
| 版本： | 原创版 |
| version： | Original |
| 分类： | 标准指南 |
| classification： | Standard guideline |
| 领域： | 综合 |
| field： | Comprehensive guideline |
| 国家和地区： | 中国 |
| Country and region： | China |
| 指南使用者： | 全国各地，各民族的健康人群和食管癌高风险人群。 |
| Guide users： | Healthy people and people at high risk for esophageal cancer in all regions of China. |
| 证据分级方法： | 对食管癌证据体采用GRADE方法进行质量评价。根据GRADE方法，将证据质量分为高、中、低、极低四个等级。在证据分级过程中，存在五个降级因素:局限性、不精确性、不一致性、不直接性以及发表偏倚和三个升级因素: 效应量大、剂量反应关系以及可能的混杂因素(负偏倚) |
| Evidence grading method： | The GRADE method was used to evaluate the quality of evidence related to esophageal cancer. According to the GRADE method, the quality of evidence is divided into high quality, moderate quality, low quality, and very low quality. In the evidence grading process, there are five downgrading factors: limitations, imprecision, inconsistency, indirectness, and publication bias, and three upgrading factors: large effect size, dose-response relationship, and possible confounders (negative bias). |
| 制定单位： | 中国人群健康风险管理协作组-食管癌专业组 |
| Formulating unit： | Chinese Health RIsk MAnagement Collaboration (CHRIMAC) - (specific disease) Group |
| 注册时间： | 2023-12-17 |
| Registration time： | |
| 注册编号： | PREPARE-2023CN363 |
| Registration number： | |
| 指南制订的目的： | 食管癌是全球第九大常见癌症，也是我国常见的恶性肿瘤之一。在我国，尽管食管癌的发病率和死亡率均呈下降趋势，但大多数病例在诊断时已为晚期，因此预后仍然较差，造成了巨大的疾病负担。食管癌的发生涉及多种因素，包括但不限于不良的生活方式、饮食习惯、遗传因素和环境暴露。本指南将对健康人群以及高风险人群的食管癌相关研究证据进行系统的梳理总结，并形成科学、全面、实用的食管癌风险管理建议，从而提供涵盖饮食、生活方式等方面的食管癌预防建议。 |
| Purpose of the guideline： | Esophageal cancer ranks as the ninth most common cancer globally and is also one of the prevalent malignancies in China. Despite a declining trend in the incidence and mortality rates of esophageal cancer in China, the majority of cases are diagnosed at an advanced stage, leading to a poor prognosis and imposing a significant disease burden. The occurrence of esophageal cancer involves various factors, including but not limited to unhealthy lifestyles, dietary habits, genetic factors, and environmental exposure. This guideline systematically reviews and summarizes research evidence related to esophageal cancer in both the general population and high-risk groups. It aims to formulate scientific, comprehensive, and practical recommendations for esophageal cancer risk management, thereby providing esophageal cancer prevention suggestions covering diet, lifestyle, etc. |
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