Consensus on the Standardization of Mycobacterium tuberculosis Drug Susceptibility Testing by Broth Microdilution plate Method in China

标题: Consensus on the Standardization of Mycobacterium tuberculosis Drug Susceptibility Testing by Broth Microdilution plate Method in China
版本: 原创版
分类: 专家共识
领域: 综合
国家和地区: 中国
指南使用者: Doctors and laboratory personnel from medical system and disease prevention and control institutions at all levels.
证据分级方法: The recommendations were attained using the Delphi voting method, where all experts involved in the consensus development voted and provided feedback. A consensus with an approval rate of ≥ 90% is classified as a strong recommendation, 75% to < 90% as a weak recommendation, and < 75% as no recommendation. The drafting committee revised the document based on the feedback, and the final version was approved by the steering committee after review.
制定单位: Fangyou Yu
注册时间: 2024-10-24
注册编号: PREPARE-2024CN048
指南制订的目的: Tuberculosis (TB), especially drug-resistant TB, is a severe public health challenge in China. Current diagnostic methods, such as phenotypic drug susceptibility testing (DST) and molecular diagnostics, have limitations either in providing accurate drug resistance profiles or detecting new resistance genes. The broth microdilution plate method (BMD plate), which measures minimum inhibitory concentrations (MICs), is gaining attention for its ability to provide more detailed drug susceptibility data, making it more effective for guiding treatment. To standardize the use of BMD in managing drug-resistant TB in China, a consensus has been developed to offer unified guidelines.