In December 2021, Zijun Wang et al. from the Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, published an article in the Journal of Clinical Epidemiology entitled "COVID-19 vaccine guidelines was numerous in quantity but many lack transparent reporting of methodological practices". The aim of the article was to describe the current status of COVID-19 vaccine guidelines published between January 1, 2020 and July 8, 2021, and to identify the problems with the guidelines in this area and to provide suggestions for future guideline development.
Threatened miscarriage is one of the most common complications of pregnancy, in recent years, threatened miscarriage occurs in about 20% -25% of all pregnant women, although mild threatened abortion can continue after rest and treatment, but most of them can eventually develop into inevitable miscarriage or incomplete miscarriage as symptoms worsen. At present, the methods of traditional Chinese medicine and integrated traditional Chinese and Western medicine in the treatment of threatened miscarriage are widely used in clinical practice and have achieved good efficacy. Clinical practice and trials have confirmed that proprietary Chinese medicine alone/in combination with Western medicine has unique advantages in the treatment of threatened miscarriage, but at present, there is a lack of evidence-based medical evidence evaluation and treatment recommendation, and there is no specific guideline or standard for the treatment of threatened miscarriage of proprietary Chinese medicine for follow-up and reference, which limits the efficacy of proprietary Chinese medicine in the treatment of threatened miscarriage to a certain extent. To this end, we have carried out the development of the "Clinical Application Guidelines for the Treatment of Threatened Miscarriage by Proprietary Chinese Medicines" in order to standardize the clinical application of proprietary Chinese medicines for the treatment of threatened miscarriages with single or combined Western medicines and improve the treatment effect.