| Purpose of the guideline: |
Infectious bone defect is bone defect with infection or as a result of treatment of bone infection. It requires surgical intervention and is a worldwide problem in the field of orthopaedic trauma. Conventionally, sequestrectomy, bone grafting or bone transport, and systemic/local antibiotic treatment are standard therapies. Radical debridement remains one of the cornerstones of the management of infection control. However, the method of bone defect reconstruction is still controversial. Bone transport technique was first reported by Ilizarov in the 1960s. This technology followed the tension-stress rule and slow distraction osteogenesis principle to repair bone defects, bringing revolutionary changes to the reconstruction of infected bone defects and becoming a milestone bone reconstruction technology in the 20th century. However, the lack of understanding the basic principles of infection control and technical details may hamper the clinical outcomes. Furthermore, lack of standardization are usually met in the treatment of infected bone defects with bone transport technique. Therefore, Orthopaedic Department, Southwest Hospital, Army Medical University, formulated this guideline based on the evidence-based method, striving to comprehensively analyze and summarize the current research results, so as to provide valuable reference information for the clinical practice of treatment of infected bone defects with bone transport technique. |
