| 标题： | 高危型人乳头瘤病毒感染中西医结合诊疗指南 |
| title： | Guidelines for the diagnosis and treatment of high-risk human papillomavirus infection using a combination of traditional Chinese and Western medicine |
| 版本： | 原创版 |
| version： | Original |
| 分类： | 中医药指南 |
| classification： | Traditional Chinese Medicine guideline |
| 领域： | 综合 |
| field： | Comprehensive guideline |
| 国家和地区： | 中国 |
| Country and region： | China |
| 指南使用者： | 中医师、中西医结合医师、西医师 |
| Guide users： | Traditional Chinese Medicine Practitioner, Integrated Traditional Chinese and Western Medicine Practitioner, Western Medicine Practitioner |
| 证据分级方法： | GRADE证据分级方法 |
| Evidence grading method： | GRADE Evidence Grading Method |
| 制定单位： | 广东省中医院（广州中医药大学第二附属医院） |
| Formulating unit： | Guangdong Provincial Hospital of Traditional Chinese Medicine (Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine) |
| 注册时间： | 2024-02-09 |
| Registration time： | |
| 注册编号： | PREPARE-2024CN263 |
| Registration number： | |
| 指南制订的目的： | 宫颈癌的发病率是全球女性恶性肿瘤的第2位，高危型人乳头瘤病毒（high risk human papilloma virus, HR-HPV）感染是导致宫颈癌发生的主要原因。预防HR-HPV 感染和对已经感染的 HR-HPV 进行及时有效干预，可使宫颈癌成为可防可治的疾病。 迄今为止，国际上暂无公认确能清除HR-HPV的药物，各种治疗方案仍处于积极探索中，临床疗效尚无法保障，因此，在循证基础上充分挖掘中西医的治疗方法，形成《高危型人乳头瘤病毒感染中西医结合诊疗指南》，对于临床规范治疗HR-HPV感染具有非常重要的意义。 本指南基于循证证据，对HR-HPV持续感染的SPI、低级别宫颈病变，及高级别以上宫颈病变经治疗后HR-HPV持续不转阴患者，制定治疗规范，以适应临床需要，为患者提供最佳的诊疗服务。宫颈、外阴、阴道的HR-HPV的感染的中西医结合治疗均可参考本指南。 |
| Purpose of the guideline： | The incidence rate of cervical cancer is the second highest among female malignant tumors in the world. High risk human papilloma virus (HR-HPV) infection is the main cause of cervical cancer. Preventing HR-HPV infection and timely and effective intervention of already infected HR-HPV can make cervical cancer a preventable and treatable disease. So far, there is no internationally recognized drug that can effectively clear HR-HPV, and various treatment options are still being actively explored. Clinical efficacy cannot be guaranteed. Therefore, based on evidence-based treatment, fully exploring the treatment methods of traditional Chinese and Western medicine, and forming the "Guidelines for the Combined Diagnosis and Treatment of High Risk Human Papillomavirus Infection" is of great significance for the standardized clinical treatment of HR-HPV infection. This guideline is based on evidence-based treatment for patients with persistent HR-HPV infection, SPI, low-grade cervical lesions, and high-grade cervical lesions who have not turned negative after treatment. Treatment standards are developed to meet clinical needs and provide the best diagnostic and treatment services for patients. The combination of traditional Chinese and Western medicine can refer to this guideline for the treatment of HR-HPV infections in the cervix, vulva, and vagina. |
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