《先兆流产中西医结合诊疗指南》

标题: 《先兆流产中西医结合诊疗指南》
title: 《 Guidelines for the Diagnosis and Treatment of Threatened Abortion with the Integrated Traditional Chinese and Western Medicine》
版本: 原创版
version: Original
分类: 中医药指南
classification: Traditional Chinese Medicine guideline
领域: 诊疗
field: Diagnosis and Treatment
国家和地区: 中国
Country and region: China
指南使用者: 临床医师
Guide users: Clinician
证据分级方法: Grade证据等级分级
Evidence grading method: Grade Evidence Grading
制定单位: 黑龙江中医药大学附属第一医院/北京大学第三医院
Formulating unit: The First Affiliated Hospital of Heilongjiang University of Chinese Medicine/Peking University Third Hospital
注册时间: 2023-02-27
Registration time:
注册编号: PREPARE-2023CN104
Registration number:
指南制订的目的: 先兆流产(threatened abortion)是妇产科常见的妊娠疾病之一 ,在妊娠女性中发生率高达25%,其中近一半最终可进展为难免流产[1],严重影响患者身心健康。对于此类患者,及时有效的治疗是继续妊娠的关键,目前补充孕激素是现代医学治疗先兆流产常用手段。祖国医学治疗先兆流产历史悠久,具有完善的理论体系,在辨证论治的基础上,结合现代医学技术,中西医协同诊治先兆流产优势日益显著。 目前国内关于胎漏、胎动不安中医诊疗指南为中华中医药学会2012年所颁布,中国医师协会生殖医学专业委员会于2021年发布了《孕激素维持妊娠与黄体临床实践指南》,这些指南均对先兆流产临床诊疗工作及提高临床诊疗水平发挥了积极作用。目前,对于先兆流产的诊治仍是专家们的研究焦点,且大量实践表明,中西医结合治疗本病颇具优势,但临床上尚缺少中西医诊疗建议,因此如何规范中医特色治疗方案,让中西医治疗方案优势互补已成为临床期待解决的问题。本诊疗指南的制定按照循证医学步骤,通过对国内外先兆流产文献进行检索,进行文献质量评价,根据GRADE分级形成推荐意见,组建制定小组,结合德尔菲法专家问卷调查,征询专家意见,形成先兆流产中西医结合诊疗指南推荐稿,从而明确中西医诊断内涵(疾病名称、诊断标准),规范中医辨证分型,规范中西医结合诊疗指南,作为现有指南的重要补充,以期进一步提高先兆流产诊疗水平、规范临床医疗行为、节约医疗资源、促进妇幼保健工作,更准确的体现中西医结合临床疗效优势,探索践行中西医结合的思路与方法,最大限度地保证治疗的规范性、科学性及可行性。
Purpose of the guideline: threatened abortion is one of the common pregnancy diseases in obstetrics and gynecology, with an incidence of up to 25% among pregnant women, nearly half of whom may eventually progress to inevitable abortion [1], which seriously affects patients' physical and mental health. For such patients, timely and effective treatment is the key to continue pregnancy. Currently, progesterone supplement is a common means of modern medical treatment of threatened abortion. The medical treatment of threatened abortion in China has a long history and a sound theoretical system. On the basis of syndrome differentiation and treatment, combined with modern medical technology, the advantages of Chinese and western medicine in the collaborative diagnosis and treatment of threatened abortion are increasingly significant. At present, the Chinese Association of Traditional Chinese Medicine issued the guidelines on the diagnosis and treatment of fetal leakage and fetal disturbance in 2012, and the Reproductive Medicine Professional Committee of the Chinese Medical Doctor Association issued the Clinical Practice Guidelines on Progesterone Maintenance of Pregnancy and Corpus luteum in 2021. These guidelines have played a positive role in the clinical diagnosis and treatment of threatened abortion and the improvement of the clinical diagnosis and treatment level. At present, the diagnosis and treatment of threatened abortion is still the focus of experts' research, and a large number of practice shows that the treatment of traditional Chinese and western medicine has advantages, but the clinical lack of traditional Chinese and western medicine diagnosis and treatment suggestions, so how to standardize the characteristics of traditional Chinese and western medicine treatment plan, the complementary advantages of traditional Chinese and western medicine treatment plan has become a clinical problem to be solved. According to the steps of evidence-based medicine, this diagnosis and treatment guideline is formulated by searching domestic and foreign literature on threatened abortion, evaluating literature quality, forming recommendation opinions according to GRADE grade, setting up a panel, and consulting expert opinions by combining the questionnaire survey of experts with Delphi method to form recommended guidelines for the diagnosis and treatment of threatened abortion. So as to clarify the diagnostic connotation of traditional Chinese and western medicine (disease name, diagnostic criteria), standardize the syndrome differentiation of traditional Chinese and western medicine, and standardize the diagnosis and treatment guidelines of integrated Chinese and western medicine. As an important supplement to the existing guidelines, it is expected to further improve the diagnosis and treatment level of threatened abortion, standardize clinical medical behavior, save medical resources, promote maternal and child health care, and more accurately reflect the advantages of clinical efficacy of integrated Chinese and western medicine. Explore and practice the ideas and methods of integrated Chinese and western medicine to ensure the normalization, science and feasibility of treatment to the maximum extent.