痴呆及相关认知障碍的神经影像学诊断专家共识

标题: 痴呆及相关认知障碍的神经影像学诊断专家共识
title: Experts consensus on neuroimaging diagnosis of dementia and cognitive impairment
版本: 更新版
version: Updated
分类: 专家共识
classification: Experts consensus
领域: 诊断
field: Diagnosis
国家和地区: 中国
Country and region: China
指南使用者: 内科医师,包括神经内科医师、认知障碍疾病专科医生和放射科医师
Guide users: clinicians, including neurologist, cognitive disorders specialists and radiologists
证据分级方法: JBI 证据推荐级别系统(2014版本)
Evidence grading method: JBI Levels of Evidence (2014)
制定单位: 上海交通大学附属瑞金医院
Formulating unit: Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
注册时间: 2022-10-25
Registration time:
注册编号: PREPARE-2022CN677
Registration number:
指南制订的目的: 近年来,随着临床实践及研究的进展,以神经影像学生物标志物为代表的临床辅助诊断技术极大的促进了痴呆及相关认知障碍的临床诊断、疾病分级、预后评估的发展,以阿尔茨海默病(Alzheimer’s disease, AD)为代表的变性性痴呆甚至已经做到了生前明确诊断。然而,遗憾的是,迄今为止,如何合理使用上述神经影像检查及合理解释检查结果以指导临床实践,还少见相关临床可操作性的方案及共识。基于以上背景,在国内多位知名痴呆及障碍疾病专家及神经影像专家紧密合作的基础上,结合自身临床实践经验及国内外最新进展,在2017版《痴呆及相关认知障碍的神经影像学诊断流程建议》的基础上,首次在国内推出了痴呆及相关认知障碍的神经影像学诊断的专家共识,并期待随着实践经验总结和研究进展,后续将不断更新和修订。
Purpose of the guideline: In recent years, with the progress in clinical practice and research, neuroimaging biomarkers has greatly promoted the diagnosis, classification and prognosis evaluation of dementia and cognitive impairment. For example,neurodegenerative dementia, especially represented by Alzheimer's disease (AD), could even been definitely diagnosed based on in vivo imaging technology rather than biopsy. However, there remains few available schemes or consensus on when to use of neuroimaging technology and how to interpret the results reasonably. Therefore, the work group, composed of many well-known experts in cognitive impairment and neuroimaging, updated former version of Advice on Diagnostic Process of Neuroimaging in Dementia and Cognitive Impairment (2017, Wang Gang) and first established this experts consensus on neuroimaging diagnosis of dementia and cognitive impairment in China based on clinical experience and latest progress in imaging research. It is expected that with the summary of practical experience and research progress, this guideline will continue to be updated and revised.