Edition: Adapted
Classification: Standard guideline
Field: Comprehensive guideline
Countries and regions: Egypt
Guidelines users: o Healthcare professionals in primary, secondary, and tertiary care of neonatal and maternity services including physicians, nurses, pharmacists, laboratory technicians.  Primary health care physicians and general practitioners  Family medicine specialists  Pediatricians  Neonatologist  Hematologists  Nurses  Blood bank specialist o Clinical Specialties  Physicians (pediatricians, neonatologists, pediatric infectious diseases, microbiologists, and obstetricians), clinical pharmacists, nurses, laboratory technicians, and midwives.
Evidence classification method: The description of the methodology for the production of this adapted CPG can be fulfilled by utilizing the ‘Adapted ADAPTE’ method. This CPG formal adaptation method includes three phases (setup, adaptation, and finalization), nine modules, and 24 steps with modifications in the steps and tools to suit the local general healthcare setting in Egypt. Overall, the steps of CPG adaptation includes the selection of the high-priority health topic, formulation of the CPG adaptation working group, identification of health questions using the PIPOH model, searching and selecting the source original CPGs with clear inclusion and exclusion criteria, quality assessment of included source CPGs by using the Appraisal of Guidelines for Research and Evaluation (AGREE) II Instrument, assessment of the currency of the selected source CPGs, drafting of the adapted CPG, external review and consultation process, finalization of the adapted CPG with a set of implementation tools, declaration of conflicts of interests, and finally a plan for review and update. For further details on the specific modifications in steps and tools, refer to the article https://doi.org/10.1111/jep.12479].
Development unit: Egyptian Pediatric Clinical Practice Guidelines Committee (EPG), Egypt.
Registration time: 2022-08-04
Registration number: PREPARE-2022CN444
Purpose of the guideline: 1) Provide an evidence-based document for the appropriate use of blood components. 2) Define indications, dosing, and administration of different blood components. 3) Safe transfusion practice including pre-transfusion testing, handling of blood component, and close monitoring of transfused patients. 4) Recommendations in special situations (multi-transfused subjects, massive transfusion, and the critically ill).